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- Volume 1, Issue 1 2026
By Faisal Ehsan, Misha khan, Rimsha Ali and Samia Imran
Keywords: Consanguinity, Cerebral Palsy, Maternal Age, Neurological disorder, Prevalence, socio economic status.
Cerebral palsy is a heterogeneous group of non-progressive motor disorders caused by brain injuries that originate in the prenatal period, perinatal period, or first few years of life. CP is classified according to the type of lesion in the brain, signs, and symptoms (spastic, ataxic, dyskinetic, and mixed CP), time of insult (prenatal, intra- natal, post- natal). Topographical involvement of limbs (hemiplegia, diplegia, or quadriplegia), changes in muscle tone (hypotonic, isotonic, hypertonic). To analyze socioeconomic factors, maternal age, and genetic predisposition in CP prevalence. A crosssectional study was conducted with 112 pediatric CP patients in Karachi. Data were collected via interviews, questionnaires, and medical records. SES, maternal age, and consanguinity were analyzed using descriptive and inferential statistics. Low SES was significantly associated with CP (p=0.001). Maternal age showed no significant association with CP risk (P>0.05). Consanguinity correlated with a higher likelihood of CP (p= 0.002). This study highlights the significant associations between socioeconomic status and consanguinity with the risk of cerebral palsy, providing valuable insights into potential risk factors for this condition, while no significant association with mother age was found.
Submission Date: 7 Mar, 2025 Reviews Completed: 5 Aug, 2025Acceptance Date: 22 Sep, 2025 Publication Date: 1 Jan, 2026